We’ve all felt it—those heavy eyelids, the afternoon energy crash, or the overwhelming desire to cancel plans and crawl into bed. Fatigue is one of the most common symptoms reported in clinical practice. But what if fatigue isn’t just an inconvenience or something to “push through”? From a naturopathic perspective, fatigue is a message—one your body is wisely sending to get your attention.

What Is Fatigue, Really?

Fatigue is more than just tiredness. Tiredness resolves with rest. Fatigue, on the other hand, lingers. It’s a persistent lack of energy that doesn’t improve with sleep alone. And it’s not always physical—it can be mental, emotional, or even spiritual.

In naturopathic medicine, we don’t just treat fatigue as a symptom. We view it as a signpost. A signal pointing toward a deeper imbalance or unmet need in the body.  In my practice I notice that patients often have 3 or more of the underlying causes of fatigue, happening simultaneously. 

Fatigue as a Health Signal

Rather than silencing fatigue with caffeine, sugar, or stimulants, we ask: What is your body trying to tell you?

Here are several key messages fatigue might be sending:

1. “I’m depleted.”

Chronic stress, poor diet, overworking, and inadequate rest can all lead to depletion. Your adrenal glands, responsible for producing stress hormones like cortisol, may be overworked—leading to “adrenal fatigue” or dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis.

Signs of depletion:

  • Wired but tired
  • Difficulty waking in the morning
  • Craving salt or sugar
  • Energy crashes after meals
  • ADD VIDEO CALLED ADRENAL FATIGUE

2. “My mitochondria are struggling.”

Every cell in your body produces energy through mitochondria. If they aren’t functioning well—due to nutrient deficiencies, toxin exposure, infections, or oxidative stress—you’ll feel it as systemic fatigue.

Common mitochondrial stressors:

  • Toxic heavy metals such as mercury, lead, cadmium, arsenic
  • Mold toxins such as aflatoxins
  • Environmental toxins such as glyphosate, or Round Up
  • Chronic viral infections such as Epstein Barr or CMV or SarsCoV-2
  • Low levels of B vitamins, CoQ10, magnesium, or carnitine

3. “I feel inflammed”

Ongoing inflammation—from autoimmunity, food sensitivities, hidden infections, or poor gut health—uses up a tremendous amount of energy. Your body may down-regulate activity to conserve resources for internal repair.

Fatigue-related causes:

  • Food intolerances (like gluten, dairy, corn, soy, egg, potato, sugar)
  • Gut dysbiosis
  • Leaky gut
  • Epstein-Barr virus (EBV) or Lyme disease
  • Autoimmune flare-ups

4. “I’m not getting the nutrition I need.”

Even a healthy diet can fall short if your body isn’t absorbing nutrients properly. Many people assume that if they’re eating well—plenty of vegetables, lean proteins, and whole foods—they’re covered. But the digestive system must break down and assimilate those nutrients, and that process is delicate and easily disrupted.

In my practice, I see this every day—particularly low stomach acid, also known as hypochlorhydria. Contrary to popular belief, acid reflux and indigestion are more often due to too little stomach acid, not too much. Stomach acid is the first domino in a long digestive cascade. It signals the release of digestive enzymes from the pancreas and bile from the gallbladder. Without enough acid, food isn’t properly broken down in the stomach, and everything downstream suffers—especially nutrient absorption.

The result? Subclinical deficiencies that don’t always show up on standard bloodwork but still have real effects. Iron, B12, calcium, magnesium, zinc, and protein—all depend on an acidic stomach environment to be absorbed efficiently.

So what causes low stomach acid? One of the most common culprits is chronic stress. When you’re in a fight-or-flight state, your body redirects energy away from digestion. This was helpful when we were running from predators—but not when we’re anxious, overworked, or scrolling before meals. Stress literally shuts down digestion. Add aging, certain medications (like antacids or PPIs), or past infections like H. pylori, and it’s easy to see how this becomes a silent epidemic.

Common signs of low stomach acid include:

  • Bloating or fullness after meals

  • Belching or gas

  • Undigested food in stool

  • Fatigue after eating

  • Weak nails or hair loss

  • Iron or B12 deficiency that doesn’t resolve with supplementation

     

Addressing this issue is foundational for energy. Supporting stomach acid production—often with simple steps like mindful eating, apple cider vinegar, bitters, or, in some cases, supplemental HCl—can radically change how you digest and feel.

 

5. “I need emotional or spiritual nourishment.”

Not all fatigue is physical. Emotional burnout, chronic dissatisfaction, lack of purpose, or unresolved grief can weigh on the body and drain energy just as powerfully as illness.

Ask yourself:

  • Am I aligned with how I spend my time?
  • Do I feel seen, heard, and connected?
  • What might I be grieving or avoiding?

Fatigue Isn’t the Problem. It’s a Clue.

Conventional medicine may stop at “normal labs” or label fatigue as depression, aging, or just something to live with. But a naturopathic lens digs deeper.

When patients come in with fatigue, I often investigate:

  • Thyroid and adrenal function (including full thyroid panel, not just TSH)
  • Nutrient status via blood work (iron, B12, vitamin D, magnesium, etc.)
  • Sleep quality and circadian rhythm
  • Toxin exposure (mold, heavy metals, chemicals)
  • Gut health and microbiome balance
  • Chronic infections or immune markers
  • Lifestyle alignment and stress load

Supporting Fatigue Naturally

True healing means addressing the root cause, not masking the symptoms. Some foundational steps include:

  • Prioritize sleep: Aim for 7–9 hours of quality rest. Avoid screens before bed, and keep a consistent rhythm.
  • Stabilize blood sugar: Eat protein-rich, fiber-filled meals and limit refined carbs and sugars.
  • Support your mitochondria: Nutrients like CoQ10, B-complex, magnesium, and L-carnitine may help.
  • Reduce inflammatory inputs: Eliminate trigger foods, manage stress, and support detox pathways.
  • Rebuild joy and purpose: Engage in activities that fulfill you and connect you to others.

Listen to Your Body—It’s Talking to You

Fatigue isn’t something to be ashamed of or ignored. It’s often one of the earliest and most compassionate ways your body asks for change. When we stop and listen—rather than push through—we open the door to true, sustainable healing.

Hi I’m Dr. Wendy Wells, a licensed Naturopathic Physician in Arizona in the United States.  I was awarded a Doctorate of Naturopathic Medicine from Southwest College of Naturopathic Medicine, now called Sonoran University. I’m a member of the American Association of Naturopathic Physicians and the Arizona Board of Naturopathic Medical Association.  I enjoy helping patients with a variety of acute and chronic issues such as thyroid issues, hormone balancing, chronic fatigue, food sensitivities, gut health, mental health, autoimmune and skin issues. My passion is finding the source beneath any health concerns, getting the body back in balance, educating patients and their communities about how the body heals itself, and setting a course for continued wellness going forward.

Reclaim Your Energy with Dr. Wells

Feeling constantly tired or low on energy? Discover the root causes of your fatigue and unlock your path to renewed vitality with a personalized consultation. Dr. Wendy Wells, a licensed naturopathic physician, will provide expert insights and tailored solutions to help you feel your best. Don’t wait—schedule your free consultation today and take the first step towards a healthier, more energetic life!